LAKE OSWEGO, OR (February 22, 2011) Fluramene™, the proprietary Fluorescein Sodium and Lissamine Green dye combination, received significant industry attention in the year 2010 from CRSToday and PCONSuperSite. 
In January 2011 crstoday.com published The Best of 2010, in which the panel of ophthalmologists voted for the top clinical advice, research, and technology of the year.
The following exert highlighting Fluramene’s™ innovative diagnostic influence within the dry eye arena was taken directly from the full article which can be viewed here.
Ocular Surface Disease Dr. McDonald voted for a comprehensive review that he said recognizes meibomian gland dysfunction (MGD) as the genesis of dry eye syndrome.10 More important, he wrote, the article describes how MGD leads to the symptoms and signs of dry eye “as well as the methodology of using fluorescein and lissamine green (soon available as Fluramene [Noble Vision Group, Eugene, OR]) to view the lid wiper epithelium along the line of Marx of the upper lid. [This information] has provided a logical and sensible path to evaluating and treating the ubiquitous but always puzzling dry eye patient. … [This is a] game-changing article for anyone treating dry eye.”
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Dr. Kelly Grosdidier references Fluramane™ in “New drugs designed to improve efficacy, compliance,” published by PCONSuperSite in November 2011.
Dr. Grosdidier recommended Fluramene, a combination of fluorescein sodium 1% and lissamine green 0.5% sterile solution in a 15-mL bottle. “The single drop makes it easier to diagnose ocular surface disease – instilling one drop in the eye vs. trying to wet the lissamine green strip,” he said. “This may make the strip a thing of the past. It’s available from EyesupplyUSA.com.”
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